TB-500

TB-500 is a synthetic fragment of Thymosin Beta-4 (TB4), a naturally occurring 43-amino-acid peptide present in virtually all human and animal cells. Thymosin Beta-4 is one of the most abundant intracellular peptides and plays a critical role in tissue repair, cell migration, and new blood vessel formation. TB-500 contains the active region of TB4 responsible for its healing properties. The peptide works primarily by upregulating actin, a cell-building protein that is essential for cell migration, proliferation, and differentiation — all critical processes in wound healing and tissue repair.

TB-500 has a unique molecular structure that gives it high mobility and the ability to travel long distances through tissues, meaning it can exert systemic healing effects regardless of injection site. This is a key advantage over BPC-157, which tends to work more locally. TB-500 has shown particular promise in healing slow-to-recover injuries like tendon and ligament damage, and has been widely used in equine medicine for decades. It also demonstrates anti-inflammatory, anti-fibrotic, and hair regrowth properties.